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Beau Lotto

Neuroscientist Beau Lotto shows how letting go of certainty unlocks adaptability, creativity, and leadership in times of rapid change.

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“I would highly recommend Beau as a keynote and collaborator. His compassion, curiosity, and captivating ideas – presented in such a compelling and digestible manner – not only have a broad appeal but can also serve as a real catalyst for positive change in both our corporate and personal lives.”

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Why you should book Beau Lotto for your next event

  • Beau Lotto delivers visually striking, interactive keynotes that help audiences rethink assumptions and act differently in uncertainty.
  • With deep academic credentials and real-world business impact, Beau bridges neuroscience, leadership, and innovation with rare clarity.
  • From TED mainstages to global corporations, Beau creates powerful shared experiences that set the tone for meaningful change.

Non-binding request for Beau Lotto

Neuroscientist, entrepreneur, and expert on perception, uncertainty, and human adaptability

The world is changing faster than ever, and success no longer comes from certainty, but from our ability to adapt. Beau Lotto is a world-renowned neuroscientist and entrepreneur who reveals that the greatest barrier to change is not technology or strategy, but perception itself. Through groundbreaking insights into how the brain constructs reality, Beau shows why moving forward means first letting go of deeply held assumptions. His talks challenge audiences to embrace doubt, explore “not knowing,” and unlock new ways of seeing, leading, and innovating. Known for visually stunning and highly engaging presentations, Beau creates memorable experiences that help people think differently and act with confidence in uncertainty.

 

Beau Lotto – Seeing the World Differently

Beau Lotto is one of the most prominent voices in the science of perception and human adaptability. His work explores how the brain makes sense of the world and why our beliefs, assumptions, and past experiences often limit our ability to change. Beau’s core message is simple yet transformative: adapting from A to B first requires moving from A to not-A. By trading certainty for curiosity, individuals and organizations expand their capacity to lead, innovate, and thrive in unfamiliar territory.

A three-time mainstage TED speaker with more than nine million views, Beau is known for talks that are visually rich, deeply interactive, and intellectually playful. His presentations are designed not just to inspire, but to change how people see themselves and the world around them. As a conference keynote, Beau is often chosen to open events, creating a powerful shared mindset that fuels collaboration and creativity throughout the program.

 

Academic Authority and Scientific Impact

Born in Seattle, Beau Lotto earned his bachelor’s degree from the University of California, Berkeley, before moving to Scotland to complete his Ph.D. in Neuroscience at the University Medical School in Edinburgh. He continued his academic career through postdoctoral fellowships in Edinburgh and at Duke University, where he was mentored by Professor Dale Purves.

Beau spent 20 years as a professor at University College London and is now a professor at the University of London, as well as a visiting scholar at New York University. Over the course of his academic career, he has mentored more than 30 undergraduate, master’s, Ph.D., and postdoctoral researchers. His lab has published over 70 peer-reviewed scientific articles across a remarkable range of disciplines, including perception, augmented and virtual reality, artificial intelligence, complex systems, architecture, design, and human behavior.

 

Lab of Misfits and Applied Neuroscience

In 2001, Beau founded the Lab of Misfits, the world’s only neuroperception creative studio that is also a functioning neuroscience lab. The Lab’s mission is to foster adaptability and creativity by studying humans “in the wild.” Using immersive design, digital technology, and rigorous neuroscientific measurement, the Lab conducts experiential experiments in theaters, museums, public spaces, and even entire cities.

Their work reveals the hidden drivers behind human decisions, creating insights that are scientifically robust, commercially valuable, and emotionally resonant. The Lab of Misfits has delivered public experiences at institutions such as London’s Science Museum and the Hayward Gallery, as well as large-scale public art installations. Past clients include Cirque du Soleil, L’Oréal, Microsoft, Edelman, and the UAE’s Crown Prince’s Court. Today, the Lab powers the neuroscience offering at Burson Cohn & Wolfe, one of the world’s largest communications firms.

 

Entrepreneurship and Augmented Reality Innovation

Beau is also the founder and CEO of Ripple Inc., a company holding five highly influential patents in augmented reality, with additional patents pending. Ripple’s technology enables immersive digital layers to be woven into physical environments, creating entirely new forms of storytelling and engagement. Projects such as Traces, Acoustigram, and W_nder demonstrate how AR can add meaning to places in ways previously impossible. Through this work, Beau sits at the intersection of neuroscience, technology, and human experience.

 

Global Speaker and Author

Beau Lotto has spoken at some of the world’s most influential stages, including the G8, World Economic Forum, Google Zeitgeist, Wired, Cannes Lions, Burning Man, and the Oslo Freedom Forum. He is a trusted keynote speaker for global organizations such as Microsoft, Google, Apple, Johnson & Johnson, Warner Music, Universal, Viacom, and Sainsbury’s.

In addition to his speaking and research, Beau is the author of Why We See What We Do, Why We See What We Do Redux, and Deviate: The Science of Seeing Differently. His work has been featured across major television, radio, and podcast platforms, and he has received multiple honors, including the Josef Albers Prize for Disruptive Innovation.

Book Beau Lotto for your event to give your audience a rare and transformative experience one that reshapes how they see uncertainty, change, and the possibilities hidden inside “I don’t know.”

Customer Reviews

5 of 5

“I would highly recommend Beau as a keynote and collaborator. His compassion, curiosity, and captivating ideas – presented in such a compelling and digestible manner – not only have a broad appeal but can also serve as a real catalyst for positive change in both our corporate and personal lives.”

5 of 5

“We cannot thank you enough for joining us at Deals Exchange. Both our clients and Partners raved about your session. In addition to your presentation, we sincerely appreciate the fact that you joined the first day of our program and took advantage of listening to our content. It was evident that you proactively tailored your content based off of what you heard — which no one does anymore. So, THANK YOU!”

5 of 5

“Beau lived up to and EXCEEDED everything that Pierre had promised me! Beau was able to engage and entertain our audience in a very important way, and, as Beau will attest, they needed a lot of engagement and energy! We had lots and lots of positive feedback on Beau’s talk, and it really started our day off on the right note.”

5 of 5

“Beau artfully challenged the perceptions of a large group of very knowledgeable and accomplished leaders. He is eloquent, humorous, and incredibly gifted at reframing people’s assumptions about what is true and what is possible, through a neuroscientific lens. Beau is the best speaker I’ve seen for helping leaders adopt the right mindset for transformation work.”

Rated 5.00/5 based on 4 customer reviews

Keynotes

Keynote by Beau Lotto:

The Challenge: The World is Changing Faster Than Ever

The only constant in life is change — and the future has never been more uncertain.

Whether driven by technology, climate shifts, political events, or global disruption, organizations everywhere must learn not just to manage change but to adapt to it.

Request a quote: Beau Lotto The Challenge: The World is Changing Faster Than Ever

Keynote by Beau Lotto:

The Problem: The Certainty Trap

Our brains are wired to resist change.

In our search for stability, we create systems that engineer out uncertainty — what Beau calls the “Certainty Trap.”

This trap is the single greatest barrier to innovation, creativity, and adaptability at both the individual and organizational levels.

Request a quote: Beau Lotto The Problem: The Certainty Trap

Keynote by Beau Lotto:

The Solution: Evolve or Die

In nature, the most successful systems are the ones that adapt.

Those that remain still, perish.

Adaptability is not just a leadership skill — it’s a survival skill.

Through the lens of neuroscience, Beau demonstrates how embracing uncertainty, rather than avoiding it, is the key to thriving in constant change.

Request a quote: Beau Lotto The Solution: Evolve or Die

Keynote by Beau Lotto:

The How: Adapting as a Way of Being

True adaptability is not a strategy; it’s a practice.

Beau teaches audiences how to “Change Well” — to move beyond reaction and develop the mindset, awareness, and perceptual agility to navigate uncertainty every day.

Request a quote: Beau Lotto The How: Adapting as a Way of Being

Keynote by Beau Lotto:

Being Better: Perceptual Intelligence

Perception underlies everything we do — how we lead, decide, collaborate, and innovate.

Behavioral change begins with perceptual change.

By becoming Perceptually Intelligent, leaders learn why they see the world the way they do and how to shift perspective to unlock creativity, empathy, and resilience.

Beau’s Spiral Process of Discovery equips teams to continually evolve and succeed when others can’t.

Request a quote: Beau Lotto Being Better: Perceptual Intelligence

Keynote by Beau Lotto:

The Results

Becoming Perceptually Intelligent drives:

  • Financial success and innovation
  • Happier, more collaborative, creative teams
  • Stronger customer and employee loyalty
  • Improved personal and organizational well-being

Perceptually Intelligent leaders create cultures that are contagious — empowering inclusion, driving creativity, and increasing retention by adding true value to people’s lives.

Request a quote: Beau Lotto The Results

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